I bathe her twice a month too. The apoquel worked so well that I tried going down to smallest possible dose. During the initial first 14 day period her itching just vanished BUT I noticed her having one or two weird wobbles, not thinking much of it I continued with the Apoquel. My Vet said it looked cancerous when she aspirated it, does not mean that it is malignant but she did sound somewhat worried and talked about the way the nuclei looked under the microscope. Mix all together and freeze in portions and Voila! This pill really worked for my dog. He takes 16 mg. daily and the scratching has almost stopped. Our 3 year old Lab started taking Apoquel on 12/15/17. In the article I list a number of alternative options to take- not requiring purchase of my scary supplement. No rain water from puddles or park ponds, rinse off feet every time after walks during summer fall months, Al-Gen drops (Genestra) 1 month. I brought her home and gave her 1 dose of 16 mg around 4PM. Its been about 21 hours since he had a pill, so Im hoping that by tomorrow morning, its out of his system. Bald from chewing, scratching bleeding, pus coming out of his eyes and chronic ear infections, bad yeast odor. Her stays showed fluid in her heart area and fluid in her lungs. Background. Is APOQUEL I called the vet and he told me to stop the medication and keep a closed eye on him. Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. We are stopping the med and taking to vet tomorrow to have full blood work done. It has been the Apoquel doing all of this, I believe. 4.Antihistamines- both natural and conventional. Fingers crossed she wont have any lasting problems from this drug. Apoquel is the culprit. Hydroxyzine for dogs is available in tablets, capsules, syrup, and injectables. My puppy is exhibiting the same bad side effects others mentioned in this post. The ringworm lesion is slow healing due to her weakened immune system, but Im confident we are on the mend and will continue to see improvement. Apoquel is an amazing Medication, I have a boston terrier and he has allergies to oak pollen and other blooming plants in the spring, he has been on apoquel severeal times throughout the past 2 years, for this condition, yes i have tried benydryl and he eats dog food with fish in it, by far apoqeul is the best medication to treat his allergies, no more itching, clear shiny coat again and is back to regular playful self, I give him 3.6 once a day and that does it, no side effects for Him. This drug is NOT a wonder drug and can kill your pet! One has had a spot on her left leg that she keeps licking and biting for 2 years. Dogs can take the medication orally, and they should follow the regimen until a. I am not a vet, just an educated pet owner who totally gets how frustrating it is to have an itchy dog. Itching caused by an allergic skin disease can be an I took her off Apoquel a few days ago.. And had blood work done.. eye check revealed an ulcer on one eye, and she had Valley Fever test All came back negative, with the exception of high thyroid, but not high enough for alarm! Here is a link to the 2011 Study: http://creative.advanstar.com/mkdv/2011/mkdv_vetbenchmarks_email0811/images/VBMZ300_preview.pdf. It started as seasonal allergies but he ended up itching all year round. I ran to the vet and asked for more$55 later, I had another months supply. Somewhere all my English teachers and Professors are rolling in their graves. But I love my dogs and if this is what happens with using Apoquel. I should have ask questions I usually do. Im not continuing the apoquel! In less than 7 days this drug killed our baby. Kind of mad at my vet that they were so casual about giving it to her again. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery, found that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably, your dog may be displaying signs of anxiety because of discomfort, Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs, Best Dog Food For Seniors With Sensitive Stomachs, Best Dog Food for Small Dogs with Sensitive Stomachs, Hydrogen Peroxide For Dogs Vomiting, Ears, Wounds, Other Issues. Of the types administered, hydroxyzine was one of the most effective. After reading these post Im convinced its the Apoquel. Thanks! Hed had Lyme vaccine every year and never had a problem. Still itching and the straw that broke the camels back was seizures. management. I thought I had found the magic drug. (Answered 2023), What Will Deter a Dog From Peeing in the House? petrified! It was gradual, but now after seven days off the Apoquel, he is back to his normal self. Dr. Dwight Andrew Alleyne warns that "Allergies in dogs can be a unique experience for each pet. You can use a Natural flea spray that has cedarwood oil, and a safe holistic powder for putting in the cracks and crevices of your house called Borax. After reading all the comments, I have decided not to take the risk of harming my dog more by this drug. My 14 year old Boston Terrier.my best friend in the world had been plagued by itching his entire life. I always use salt water and E5 cream or take him to the sea side so he can put his paws in to the sea and it worked late time. Along with this, came the increased urination. Try the new diet for 4 weeks. I was assured this drug was safe. The mechanism of action is thought to be similar to that of other Janus kinase inhibitors, which block the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response, she says. I hate that we now must take him off the medicine because he has been able to live a more comfortable life, but I cant ignore the side effects and how its affecting him. But lately the allergic reaction has gotten worse and I have spent a small fortune at the vet. I now wonder if he had environmental allergies. please do not give your pets this drug. I hearing some of the same things over and over with this drug. of $0.40, Increased 13% and 11%, respectively with her vet for a nail clipping. Everything looked fine but her liver enzymes were elevated. A typical dose is 1 mg per pound in dogs every 6-8 hours. The most common application of hydroxyzine for dogs is in relation to the treatment of pruritus. I hope you dont still practice medicine. Finally after several hours he ate his food and drank enough water. I am so grateful to have finally found something that works and is healthy for her. It has a different mechanism of action than steroids, cyclosporine, antihistamines, allergy shots and sublingual immunotherapy. He was diagnosed with severe pancreatitis. Shes been fine since I took her off of it. So hard to do and they dont even care as long as they make their money at $200 a bottle take it vantage of court animals and people. I found out about this drug here and on other web sites. We stopped giving him the poison on the fifth day. Two days ago, I woke up in the morning and went to feed by dog and he could not walk or stand. I called the vet but they said she must have eaten something to cause it. APOQUEL (oclacitinib) manufactured by Zoetis, I thought we were going to lose him. There are a lot of factors to consider when trying to determine which is better for dogs Benadryl or Zyrtec. Im just sick. Two days after being on Apoquel, we noticed less itching. She has had none of the issues above. Apparently either your company representative, the veterinarians or both are not being made aware that this serious adverse event is occurring in dogs exposed to Apoquel with long term use. Although there is no way of knowing for certain if the drug Apoquel is responsible for what I am seeing with my dog, I am going to stop the drug altogether. My 7 year old male GSD has been on apoquel for 2+ years now for horrible scratching due to atopic dermatitis. Fourth Quarter 2014 Revenue of $1.3 Billion Increased 5% Compared to Fourth Quarter 2013 Apoquel is a medication that is used to treat allergies in dogs. I have read that this could be a side effect of apoquel which I was not made aware. My dog was given this because it was said to work faster. Low numbers of dogs in the studies developed demodicosis, neoplasia, pneumonia, bloody diarrhea, skin and ear infections . P.S. Her body was like a noodle. After two months and weight gain and labored breathing on steroids Ollie still has this yeast infection. immune-mediated disease. Apoquel incidentally never stopped her itching and I will never resume the Apoquel. He also gets half a Zyrtec morning and night. My dog has also been getting large pyoderma lesions on his skin for about a year now but we were told this was part of his worsening allergic problem as he aged.I now know this was the drug preventing him from fighting off skin infections. The meds worked for 3 days of clearing his itching and swollen eyes but then the vomiting, not eating, stomach pains, panting, not drinking, exhaustion, completely out of it wondering and hiding in corners, didnt open his eyes for 3 days, and death happened. Its not a perfect answer, but with some experimentation this drug is helping us keep him comfortable and from blowing up and getting infected areas. Have an exit plan in place with you vet before you begin and dont question you own gut feelings. killing your If the wind blows the wrong way she starts breaking out. Plus wipe those feet after being out. I have three Shih Tzu on Apoquel for three months. At the advise of a new vet we put her on Apoquel. I watch the Zeljanz commercial which is basically a very similar drug for humans.listening to all the huge long list of potential side effects.cancers have happened and they say it like potential for thunderstormslike no big deal. Nothing worked. However, after about a month and a half our four year old dog started vomiting and was extremely lethargic. Please, please be very cautious when using this drug on your babies.. Our dog Aries who is now 12 years old suffered with severe itching and allergic type reactions that appeared to start in 2016. We drove her tp the vet which advised us that her pancreas was way over the chart as well as her liver enzymes and showed to have a severe infection that her body could not fight off. Where do you find these complaints on the site? He looked miserable like he might be dying. Seonaid, what dose are you giving your westie? Cefpodoxime (brand names Simplicef and Vantin ) is an oral antibiotic used to treat certain skin infections in dogs. Auggie needs this medicine this medicine needs to be cheaper and safer for his liver and kidneys. I at least know for sure 1 drug I would Never Try and that is this Apoquel !! He had been off and on apoquel for the last 3 years with recently consistently for the past 3 months. 2 packs of apoquel tablets Two days later he was at deaths door. I also wonder if advantix 2 would be responsible for his rash. Please do not give your dog this medicine I know it makes him stop itching but the outcome is not worth it putting him to sleep, its like putting your child asleep. Thankful that I followed my instinct as the vet made us very uncomfortable with his rapid sales pitch. Suddenly developed severe anxiety / up all night / only happy in open air park. I think I will try those probiotic and omegasits worth a shot. I am planning on trying to wean him off the Apoquel as soon as I feel he is stable. One morning about 5AM she woke me standing up on the bed and she froze and fell off the bed like a statue and had a seizure. She began taking it in Nov. Of 2019. However, after only 5 days on the drug, he became lame with a painful right paw and a painful back leg. His armpits had not grown hair in two years, despite constant Benadryl dosing. He was on it for 24 days and because of a loss of energy and frequent drinking and peeing, we decided to take him off it. While the exact mechanism of action is not known, it is thought that Apoquel works by inhibiting the activity of Janus kinase enzymes, which are important in signal transduction in many cells, including those involved in the allergic response. Norman weighs roughly 20 pounds, so he takes a 5.4mg pill. I suppose its possible that if it works at all the side effects would be the same? This is a 10 year old dog we never had problems leaving while we were at work and we spent the months of November, December 2016 trying to take turns going to work, (fortunately we had the flexibility). I am reading these comments and cannot believe why this drug is still being prescribed. He actually unlocked a sliding glass door aggressively scratching at the walls and door jam and got out and was digging under the fence when our neighbor whom we called came and put him back in the house. This is sad. Hydroxyzine belongs to a family of drugs called antihistamines. It has been launched with much fanfarefrom Zoetis.. FDA Approves APOQUEL (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs, Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation Associated with Allergic Skin Disease in Dogs. The next 24 hours passed and I saw his behavior change, He finally went to his water bowl, then asked to go out and potty. I am giving my own allergic dog an oatmeal shampoo weekly. A huge shout to today's VetGirl guest blogger is by Dr. Nicole Heinrich, DACVD of McKeever Dermatology Clinics. Research has found an ingredient known as praline-rich polypeptide (PRP) in bovine colostrum; it appears to be what is helping decrease the allergy symptoms. Thats why I blame Apoquel. She was refusing to eat out of her bowl which was a red flag because our cocker spaniel is OBSESSEd with food ( I think she likes food more than she likes us ?). We also have trazodone from her past vet (we switched 6 months ago) for her bad car/boarding anxiety. Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs. She is licking herself just as much as she did before and she get some kind of black spots on her body, and her skin is full of small scales of dried skin which she never had before. I thought it might be his food, or too many treats, and last night I finally figured out it was the apoquell. For the most part hes back to being our happy, playful puppy. He was going to go back onto Apoquel after being off it for a short time. He had been on it continually for about two/three years as I was I informed that there was no serious side effects and that it could be used for as long as it was working. Vet said it was not the Apoquil. I ended up at the emergency hospital where he was put on antibiotics, IVs and had X-rays, bloods and ultrasounds done. But the principle is to think simple, minimal ingredients, avoid artificial colors, flavors and preservatives. animals own cells. Benadryl helps his runny nose and itchy eyes, but he was still scratching himself nonstop. Anything that prevents the immune system from functioning properly is dangerous. Not sure it will make a difference or if they even care, but I hope this message will bring hope to others who are currently experiencing the downside to Apoquel. Antihistamines are over-the-counter so they have a . Redness . My 4yo Yorkie has been on Apoquel for 5 months. I certainly want her to be happy but also healthy. Apoquel should be given orally to your dog as a pill twice daily for the first 14 days, then reduced to once daily for maintenance. For the prescriptions !!! Its crazy how fast that can happen. Hello, I have 2 german shepherds. His skin is scaley and flakes like crazy. But not at the cost of seizures. dog? I have two westies on apoquel, both have problem skin. frequent bathing, washing feet frequently etc. 2 days ago, on daily dosing st this point, he had another. It may be given with or without food, but giving it with food may reduce the chances of GI side effects. What drugs should not be taken with Apoquel? My dog was on Apoquel for several months. No drug is totally safe. We purchased a bottle with 70 tablets for $137.20 in hopes that this would provide some relief. Eating and drinking well but started soiling in the house. Ill try it too. Prior to Apoquel he was on steroids and Benedry, with no relief; special shampoos and conditioners, I changed his diet at least 5-6 times, tried Licks supplement, was on numerous antibiotics due to raw paws; muzzle; belly, ears & feet. Dogs who have a weight of 10 to 14.9 lbs should be given 5.4mg tablets daily and two times. Hes on IV fluids but not expected to live more than a week. We just make sure to take him out frequently to be safe. We were introduced to Apoquel because our Red Long Haired Doxie was having allergies that were causing her to hack and cough so hard it gave her nose bleeds and it was causing anal gland problems. She has been on it for about 3 weeks now. Vet suggested Apoquel. Then he began acting weird one day starting with having diarrhea then he started panting, drooling, pacing, sitting on my chest I knew something was wrong and went to the animal emergency room. Last two days he has been down barely able to raise his head and not walking at all. start with the lowest possible dose and increase gradually if needed. We tried everything with no resolve. Such as, what is the correct hydroxyzine dosage for dogs? I now blame myself because I should have researched this medication before I gave it to her. About 30 minutes later, I woke up to find her sitting up in the bed just staring off into space and whining. Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. She is Am. I will also take my other boy off this medication. E-mail: rfisher1951@yahoo.com If that was my dog, I would NOT ever give him those pills. Tavist and chlortrimeton Even though dogs and cats produce their own vitamin c, (we humans as you know do not) are you aware of anyone trying this approach in the animal world? It contains essential fatty acids, probiotics, and colostrum, but more importantly it has helped thousands of dogs. After 1 month she was reduced to 1 in the morning. My 15 year old Cairn developed environmental allergies when she moved to CT from FL. This is also holistic and works by making the yeast exit the body through the hair follicles. He has urinated in front of me, also not wanting to stay outside, or even go outside. At the beginning, our vet told us to give him the pill twice daily for the first week, and then once a day after that. She has been on 3 primary seizure drugs used in humans for almost a year now. Apoquel works for most pets but not all. Well after about 4 mths I couldnt take it anymore. Multiple doses of antibiotics for skin infections. He will not walk againthey think the infection is in his spine now. My story started a year ago last august when he scratched his jaw bloody on both sides. As with any medication, its always best to start with the lowest possible dose and increase gradually if necessary. He is 25 lbs (huge westie, I know), and I have found that if I give him 1/4 pill in the morning that the side effects go away and itching is pretty much under control. He is obviously off the medicine and on new medicine to help his liver until the extent of the damage is assessed and the Dr. can provide a treatment plan moving forward. Today Im contacting the FDA to self report these side effects. and said everything is normal, probably will never happen again. You can continue to treat your dog with APOQUEL for as long as your veterinarian recommends. They are making Millions off this.?? On day 19 and 21 i noticed she peed the bed when Id been out(never ever done that before) Stellas diet is I bunch of spinach, 4 carrots, I head of broccoli and 4 sticks of celery, raw, blitz it up in a food processor, add 5 boiled eggs, shells included. Dog parent of 8 yrs, we just moved from VA to NC in the winter season. Drugs.com is where I found all the horrible side effects of the drug and it was too late. A little research showed that the Rx was twice the recommended amount for her. You wont see an instant response, but you may see some marked decrease in allergic signs after using probiotics for 4 weeks. You can contact Zoetis Inc at 1-888-963-8471. THOUGHT OF THAT UNTIL IT WAS TOO LATE. We are devastated. But just a few days later she was falling and pacing and panting. Apoquel is an allergy medication while Benadryl is an antihistamine. She played and ate normally that evening and we turned in at our usual bedtime of 9:30. Without that terrible Apoquel. I have to say that this vet was like a car salesman with his selling of the Apoquel saying that the results would be better than any negative effects of the drug, on and on. Go ahead with apoquel. Apoquel is the only thing that has worked. This is how hydroxyzine is used on humans. Not sure! So, on Apoquel she went. Hi. Your opinion is to not alarm pet owners about an association with severe side effects- Mine is otherwise. IF your dog has allergies, he needs to be on these. Active and happy. After allergy, blood and urine tests she put him on Apoquel, 2 times a day for 1 week and then one pill in morning. United States which showed that APOQUEL was effective in the treatment of pruritus God knows how he pulled through but after 5 days he was on a turn in the right direction. Also KU Medical center, dept of Integrative Medicine. Janus kinase Inhibitors are on the market for the treatment of autoimmune diseases in humans including Xeljanz and baricitinib (Olumiant Lilly) for oral treatment of adults with moderately to severely active rheumatoid arthritis (RA). She is now on hydroxizine and it is at least as effective without the immune suppression and horrible risks. O.K its very late and a long stress filled day When I looked them up I immediately stopped the drug but it was too late. 3.Regular bathing- of your dogs feet as he comes in from outside, and of your entire dog. Making her sick. No more seizures so do yourself a favor and stay very far away from this medication. Sick part about it is I believe they make this drug for people too. She has kept me awake for the last few nights constantly getting up and wandering because she feels so sick. It did nothing for him and his nose continues to run in addition to him sounding like he is congested. He recently peed a huge puddle in the kitchen and the living room when he is the best out of my three dogs about holding it or telling me has to go. The medication is available in tablet form in the following doses: 10 mg; 25 mg; and 50 mg. So after $1,100. She was allergic to grass and any food that was not grain free. Histamine and the antiallergic antihistamines: a history of their discoveries. Im convinced this drug killed my baby girl. In addition to Allergies Atopy, and My vet says its allergies causing it. For example, it can counteract the effects of warfarin. My miniature schnauzer had the uncontrollable itchiness and smell that went with it. Or pups under 12 months old. BUT dont consider this pill the answer. I am taking my dogs off of this. Which is better for dogs Benadryl or Zyrtec? However, it is not recommended that you do so. My vet has referred us to a vet specialist, which I hear is very expensive. He never does that, he always tells me when he has to go out. Our dog will stand at the door if he needs to go out (he wasnt taught that). No way will I us it.Thank you every one for opening my eyes. These conditions, as a group, are called He refused to eat or drink water for hours. Ive tried everything to ease her itching, and shes been on hydroxyzine for a few years with limited success. Thats terrible! As always, if you have any further questions or concerns, please do not hesitate to contact us. Karen. Apoquel is safe to use in dogs one year and older. The Vitamin C dose is 100mg per 10lbs twice daily. diarrhea, vomiting, and lethargy that resolved spontaneously in 90% of cases and did not What are the side effects of hydroxyzine in dogs? Two days ago he began vomiting, lethargy and dehydration. In the summer when his allergic signs are more common, I am bathing him twice a week. DO NOT GIVE THIS MEDICINE TO YOUR ANIMAL. Atopic dermatitis is one of the most common allergies in dogs, affecting approximately So, its impossible to recommend across the board dosages that will produce good results. This drug should be taken off the market! besides, hes strong and healthy overall, maybe a little miserable at times but we could live with that.
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